Guidelines:

The INADcure Foundation is currently accepting Letters of Intent for our Research Grants Program.

Our funding is open to:

We solicit scientific proposals to study diseases related to PLA2G6, including Parkinson’s disease. Researchers, clinicians, and postdoctoral fellows from Australia, Japan, Korea, Taiwan, most European countries (including Israel), Canada and the US are encouraged to apply.

Teams working together and based in different institutions (private or public) are strongly encouraged.

Research proposals are $150,000 max per year for two years whereas postdoctoral fellowships are $75,000 max per year for two years.

Letters of intent are due by May 1 , 2019 and will be evaluated before July 1. Selected projects will submit research grants by September 1, 2019.

Our Research Goals:

PLA2G6-related neurodegeneration (PLAN) is an umbrella term of three diseases caused by PLA2G6 loss. Infantile Neuroaxonal Dystrophy (INAD) is typically recognized in early childhood between the ages of 6 months and 2 years. A common pattern in young children is loss of previously acquired skills, mental and physical ability and progression of the disease over time. Atypical or Juvenile Neuroaxonal Dystrophy (aNAD) affects children at around age 4. The symptoms of individuals with aNAD are fairly stable during their early childhood but start declining between the ages of 7 and 12. A third, form affects young adults who develop dystonia-parkinsonism. There is currently no cure for these diseases.

The INADcure Foundation is seeking to support research for the treatment and a cure for INAD and other forms of PLA2G6-related neurodegeneration. Proposals are expected to advance our basic knowledge about the molecular and pathological mechanism of INAD/PLAN, investigate the molecular links between INAD/PLAN and Parkinson’s disease, develop genetic or other therapeutic strategies, and generate critical resources for the research community.

The first step in the process of a grant application to the INADcure Foundation is to submit a Letter of Intent (LOI) by May 1. Applicants with high potential research projects will be invited to submit a full proposal and instructions will be forwarded along with the invitation.

Instructions for the LOI:

Please provide a brief summary of the preliminary data and provide an outline of the project. Letters will be evaluated to determine the relevance of the proposed project to the Foundation’s mission. The information provided in the letter of intent should be written in lay terms. The LOI should be 2 pages in length and include the following information:

1. Project Title
2. PI and Co‐PIs, and associated institutions
3. Abstract/Summary of project
4. Major objectives
5. Preliminary data
6. Specific aims
7. Impact or expected outcomes
8. Timeline with anticipated milestones (brief)
9. Budget/Funding Amount

Interested applicants are encouraged to contact Leena Panwala, INADcure Foundation President, at info@INADcure.org with any questions prior to submitting an LOI.

Please submit your LOI along with any relevant attachments to: info@INADcure.org. A representative from the Foundation will respond to your email to confirm receipt.